MOTS-C (10mg)

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a synthetic 16-amino acid mitochondrial-derived peptide (sequence: MRWQEMGYIFYPRKLR), encoded by a short open reading frame in the mitochondrial 12S rRNA gene.

MOTS-c acts as a key regulator of metabolic homeostasis, translocating to the nucleus under stress conditions to modulate adaptive gene expression, primarily through AMPK activation and the folate-purine pathway. It enhances glucose uptake, insulin sensitivity, lipid metabolism, and mitochondrial function, while promoting exercise-like benefits such as improved physical performance and muscle homeostasis. Levels decline with age, making it a prominent focus in preclinical research on aging, obesity, insulin resistance, diabetes, metabolic disorders, and age-related physical decline.

FOR RESEARCH AND LABORATORY USE ONLY. NOT FOR HUMAN CONSUMPTION. NOT FOR MEDICAL, VETERINARY, OR HOUSEHOLD USE.

Pure Research Peptides LLC provides this compound strictly for in-vitro laboratory research purposes. No statements on this site have been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Buyer assumes full responsibility for compliance with all applicable laws and regulations.